Basement zone antibodies in bullous pemphigoid
RE Jordon, EH Beutner, E Witebsky, G Blumental… - Jama, 1967 - jamanetwork.com
Indirect immunofluorescent (IF) staining revealed that in 14 of 16 patients with active lesions
of bullous pemphigoid the sera contained antibodies specific for the basement zone
beneath stratified squamous epithelium while the sera from six patients in remission
contained no demonstrable antibodies. The sera of 18 patients with dermatitis herpetiformis
and 94 patients with various bullous and nonbullous dermatoses yielded negative reactions
to the basement zone by indirect IF staining. In four of five skin biopsy specimens from …
of bullous pemphigoid the sera contained antibodies specific for the basement zone
beneath stratified squamous epithelium while the sera from six patients in remission
contained no demonstrable antibodies. The sera of 18 patients with dermatitis herpetiformis
and 94 patients with various bullous and nonbullous dermatoses yielded negative reactions
to the basement zone by indirect IF staining. In four of five skin biopsy specimens from …
