Genetic polymorphisms and the fate of the transplanted organ

B Krüger, B Schröppel, BT Murphy - Transplantation reviews, 2008 - Elsevier
There has been an abundance of publications describing genetic variability in molecules
affecting innate and adaptive immunity, pharmacogenetics, and other nonimmunological
factors like the renin-angiotensin aldosterone system, coagulation, and fibrosis markers.
Studies indicated some associations between polymorphisms in these candidate genes with
outcomes in organ transplantation and underlined a potential role of genetic variability in
transplantation. To be clinically applicable, large prospective studies must be performed to …