Localization and characterization of endothelin receptors in human gliomas: a growth factor?
M Kurihara, A Ochi, T Kawaguchi, M Niwa… - …, 1990 - journals.lww.com
Localization and characterization of endothelin receptors in surgical specimens of human
gliomas (6 benign astrocytomas and 7 glioblastomas multiforme) and in normal human
cortices were studied using quantitative receptor autoradiographic methods. Low numbers
of [125 I] endothelin-1 ([125 I] ET-1) binding sites were detected in the gray matter of the
human frontal cortex, with little binding in the white matter. Conversely, relatively high
numbers of [125 I] ET-1 binding sites were homogeneously present in tissue sections …
gliomas (6 benign astrocytomas and 7 glioblastomas multiforme) and in normal human
cortices were studied using quantitative receptor autoradiographic methods. Low numbers
of [125 I] endothelin-1 ([125 I] ET-1) binding sites were detected in the gray matter of the
human frontal cortex, with little binding in the white matter. Conversely, relatively high
numbers of [125 I] ET-1 binding sites were homogeneously present in tissue sections …
