A novel malaria protein, Pfs28, and Pfs25 are genetically linked and synergistic as falciparum malaria transmission-blocking vaccines
PE Duffy, DC Kaslow - Infection and immunity, 1997 - Am Soc Microbiol
PE Duffy, DC Kaslow
Infection and immunity, 1997•Am Soc MicrobiolAntibodies to Pfs28 block Plasmodium falciparum transmission and when combined with
antibodies to Pfs25 provide synergy in blocking transmission. Pfs28 and Pfs25 are
immunogenic, have limited antigenic diversity, and are structurally similar and genetically
linked on chromosome 10. Pfs28 may prove a useful addition to Pfs25 in an effective
transmission-blocking vaccine.
antibodies to Pfs25 provide synergy in blocking transmission. Pfs28 and Pfs25 are
immunogenic, have limited antigenic diversity, and are structurally similar and genetically
linked on chromosome 10. Pfs28 may prove a useful addition to Pfs25 in an effective
transmission-blocking vaccine.
Antibodies to Pfs28 block Plasmodium falciparum transmission and when combined with antibodies to Pfs25 provide synergy in blocking transmission. Pfs28 and Pfs25 are immunogenic, have limited antigenic diversity, and are structurally similar and genetically linked on chromosome 10. Pfs28 may prove a useful addition to Pfs25 in an effective transmission-blocking vaccine.
American Society for Microbiology